MMP25 抗体
Quick Overview for MMP25 抗体 (ABIN7242293)
抗原
See all MMP25 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human MMP25
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亚型
- IgG
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anti-Matrix Metallopeptidase 25 (MMP25) (AA 350-540) antibody
MMP25 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 25 (MMP25) (AA 108-313) antibodyMMP25 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 25 (MMP25) (AA 108-313) antibodyMMP25 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C6 unconjugated
anti-Matrix Metallopeptidase 25 (MMP25) (Internal Region) antibodyMMP25 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- MMP25 (Matrix Metallopeptidase 25 (MMP25))
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别名
- MMP25
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25.
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分子量
- 63 kDa
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NCBI登录号
- NP_071913
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UniProt
- Q9NPA2
抗原
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