ELAC2
适用: 人
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 594
应用备注
WB 1:500-1:2000
限制
仅限研究用
状态
Liquid
浓度
0.7 mg/mL
缓冲液
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
ELAC2
(ElaC Homolog 2 (ELAC2))
别名
ELAC2
背景
The protein encoded by this gene has a C-terminal domain with tRNA 3′, processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.