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SYT4 抗体

This anti-SYT4 antibody is a 兔 多克隆 antibody detecting SYT4 in WB, ELISA 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7240289
发货至: 中国

Quick Overview for SYT4 抗体 (ABIN7240289)

抗原

See all SYT4 抗体
SYT4 (Synaptotagmin IV (SYT4))

适用

  • 31
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人, 小鼠, 大鼠

宿主

  • 27
  • 6

克隆类型

  • 28
  • 5
多克隆

标记

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  • 1
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This SYT4 antibody is un-conjugated

应用范围

  • 18
  • 17
  • 7
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  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human SYT4

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:25-1:100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SYT4 (Synaptotagmin IV (SYT4))

    别名

    SYT4

    背景

    Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.

    分子量

    48 kDa

    UniProt

    Q9H2B2

    途径

    Synaptic Membrane, Synaptic Vesicle Exocytosis
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