TMPRSS11F 抗体
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北京 101111
Quick Overview for TMPRSS11F 抗体 (ABIN7239527)
抗原
See all TMPRSS11F 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human TMPRSS11F
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:25-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TMPRSS11F (Transmembrane Protease, Serine 11F (TMPRSS11F))
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别名
- TMPRSS11F
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背景
- TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.
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分子量
- 49 kDa
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NCBI登录号
- NP_997290
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UniProt
- Q6ZWK6
抗原
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