Sortilin 1 抗体
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北京 101111
Quick Overview for Sortilin 1 抗体 (ABIN7239479)
抗原
See all Sortilin 1 (SORT1) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human SORT1
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:35-1:150
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.7 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Sortilin 1 (SORT1)
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别名
- SORT1
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背景
- This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail.
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分子量
- 92 kDa
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NCBI登录号
- NP_002950
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UniProt
- Q99523
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途径
- Neurotrophin Signaling Pathway
抗原
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