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LASS4 抗体

This anti-LASS4 antibody is a 兔 多克隆 antibody detecting LASS4 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7239164
发货至: 中国

Quick Overview for LASS4 抗体 (ABIN7239164)

抗原

See all LASS4 (CERS4) 抗体
LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

适用

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宿主

  • 28
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克隆类型

  • 28
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多克隆

标记

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This LASS4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human CERS4

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

    别名

    CERS4

    背景

    The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.

    分子量

    46 kDa

    NCBI登录号

    NP_078828

    UniProt

    Q9HA82
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