IPO7 抗体
Quick Overview for IPO7 抗体 (ABIN7239092)
抗原
See all IPO7 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human IPO7
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亚型
- IgG
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anti-Importin 7 (IPO7) (AA 950-1038) antibody
IPO7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Importin 7 (IPO7) (C-Term) antibodyKO Validated IPO7 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Importin 7 (IPO7) (AA 142-169), (N-Term) antibodyIPO7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB26876 unconjugated
anti-Importin 7 (IPO7) (AA 1-50) antibodyIPO7 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:100-1:300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IPO7 (Importin 7 (IPO7))
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别名
- IPO7
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背景
- The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
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分子量
- 120 kDa
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NCBI登录号
- NP_006382
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UniProt
- O95373
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途径
- Protein targeting to Nucleus
抗原
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