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Aconitase 1 抗体

The 兔 多克隆 anti-Aconitase 1 antibody (ABIN7238480) specifically detects Aconitase 1 in IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7238480
发货至: 中国
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Quick Overview for Aconitase 1 抗体 (ABIN7238480)

抗原

See all Aconitase 1 (ACO1) 抗体
Aconitase 1 (ACO1)

适用

  • 113
  • 55
  • 51
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 116
  • 3
  • 1

克隆类型

  • 106
  • 14
多克隆

标记

  • 46
  • 14
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This Aconitase 1 antibody is un-conjugated

应用范围

  • 104
  • 39
  • 29
  • 26
  • 25
  • 24
  • 19
  • 18
  • 9
  • 8
  • 7
  • 3
  • 2
Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human ACO1

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.4 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Aconitase 1 (ACO1)

    别名

    ACO1

    背景

    Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.

    NCBI登录号

    NP_002188

    UniProt

    P21399

    途径

    Transition Metal Ion Homeostasis
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