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F13A1 抗体

The 兔 多克隆 anti-F13A1 antibody is suitable to detect F13A1 in samples from 人, 小鼠 和 大鼠. It has been validated for IHC 和 ELISA.
产品编号 ABIN7238432
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for F13A1 抗体 (ABIN7238432)

抗原

See all F13A1 抗体
F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

适用

  • 111
  • 8
  • 7
  • 3
  • 3
人, 小鼠, 大鼠

宿主

  • 79
  • 32
  • 3
  • 1

克隆类型

  • 61
  • 54
多克隆

标记

  • 56
  • 9
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
This F13A1 antibody is un-conjugated

应用范围

  • 71
  • 58
  • 46
  • 41
  • 32
  • 19
  • 19
  • 14
  • 10
  • 8
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human F13A1

    亚型

    IgG
  • 应用备注

    IHC 1:100-1:300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.1 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

    别名

    Factor XIIIa

    背景

    This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

    NCBI登录号

    NP_000120

    UniProt

    P00488
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