SRGAP3 抗体
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北京 101111
Quick Overview for SRGAP3 抗体 (ABIN7237712)
抗原
See all SRGAP3 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human SRGAP3
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亚型
- IgG
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anti-SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3) (AA 709-955) antibody
SRGAP3 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3) (AA 956-989), (C-Term) antibodySRGAP3 适用: 人 WB 宿主: 兔 Polyclonal RB53248 unconjugated
anti-SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3) (N-Term) antibodySRGAP3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:25-1:100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SRGAP3 (SLIT-ROBO rho GTPase Activating Protein 3 (SRGAP3))
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别名
- SRGAP3
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背景
- SRGAP3 is a 1099 amino acid protein containing 1 FCH domain, 1 Rho-GAP domain and 1 SH3 domain. Expressed highly in brain, and in lower levels in kidney, WRP is thought to play a role in cell migration through its interaction with Cdc42 and Rac1. Cdc42 and Rac1 are two intracellular signaling proteins that regulate the multistep cell migration process. WRP downregulates Cdc42 and Rac1 activity, thereby impairing actin and microtubule dynamics, the formation of protrusions, and total cell migration. Defects in the gene encoding WRP have been linked to severe idiopathic mental retardation. Three isoforms of WRP exist as a result of alternative splicing events.
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UniProt
- O43295
抗原
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