hras1 antibody, MGC78972 antibody, MGC132298 antibody, RASSF7 antibody, C11orf13 antibody, HRAS1 antibody, HRC1 antibody, 2400009B11Rik antibody, AW210608 antibody, RGD1306244 antibody, Ras association domain family member 7 antibody, Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 L homeolog antibody, Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 antibody, RASSF7 antibody, rassf7.L antibody, rassf7 antibody, Rassf7 antibody
背景
RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid protein that localizes to the centrosome. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis. Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis.