Dynactin 4 抗体
Our Local Distributor
北京 101111
Quick Overview for Dynactin 4 抗体 (ABIN7236798)
抗原
See all Dynactin 4 (DCTN4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- Polyclonal Antibody
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant protein of human DCTN4
-
亚型
- IgG
-
-
-
-
应用备注
- IHC 1:100-1:300
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.9 mg/mL
-
缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Dynactin 4 (DCTN4)
-
别名
- DCTN4
-
背景
- Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
-
UniProt
- Q9UJW0
抗原
-