ASB2
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy3
应用备注
IHC 1:25-1:100
限制
仅限研究用
状态
Liquid
浓度
0.7 mg/mL
缓冲液
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store at -20°C. Avoid freeze / thaw cycles.
抗原
ASB2
(Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))
别名
ASB2
背景
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.