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AURKAIP1 抗体

AURKAIP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7236305
发货至: 中国
  • 抗原 See all AURKAIP1 抗体
    AURKAIP1 (Aurora Kinase A Interacting Protein 1 (AURKAIP1))
    适用
    宿主
    • 16
    • 2
    克隆类型
    • 17
    多克隆
    标记
    • 4
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    This AURKAIP1 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 3
    • 3
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    • 2
    Western Blotting (WB), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human AURKAIP1
    亚型
    IgG
    Top Product
    Discover our top product AURKAIP1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    AURKAIP1 (Aurora Kinase A Interacting Protein 1 (AURKAIP1))
    别名
    AURKAIP1 (AURKAIP1 产品)
    别名
    zgc:171708 antibody, AIP antibody, AKIP antibody, 0610033H09Rik antibody, Aip antibody, Akip antibody, aurora kinase A interacting protein 1 antibody, AURKAIP1 antibody, aurkaip1 antibody, Aurkaip1 antibody
    背景
    AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
    分子量
    22 kDa
    UniProt
    Q9NWT8
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