ELP2 抗体
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北京 101111
Quick Overview for ELP2 抗体 (ABIN7236188)
抗原
See all ELP2 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human ELP2
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亚型
- IgG
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应用备注
- IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.4 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- ELP2 (Elongator Acetyltransferase Complex Subunit 2 (ELP2))
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别名
- ELP2
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背景
- One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.
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UniProt
- Q6IA86
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途径
- Stem Cell Maintenance, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
抗原
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