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CRYAB 抗体

This anti-CRYAB antibody is a 兔 多克隆 antibody detecting CRYAB in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7235811
发货至: 中国

Quick Overview for CRYAB 抗体 (ABIN7235811)

抗原

See all CRYAB 抗体
CRYAB (Crystallin, alpha B (CRYAB))

适用

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人, 大鼠, 小鼠

宿主

  • 142
  • 45
  • 2
  • 1

克隆类型

  • 137
  • 53
多克隆

标记

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  • 1
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This CRYAB antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human CRYAB

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CRYAB (Crystallin, alpha B (CRYAB))

    别名

    Crystallin-alpha B

    背景

    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone.

    分子量

    20 kDa

    UniProt

    P02511
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