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Annexin VII 抗体

This anti-Annexin VII antibody is a 兔 多克隆 antibody detecting Annexin VII in IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7234624
发货至: 中国

Quick Overview for Annexin VII 抗体 (ABIN7234624)

抗原

See all Annexin VII (ANXA7) 抗体
Annexin VII (ANXA7) (Annexin A7 (ANXA7))

适用

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人, 小鼠

宿主

  • 60
  • 3
  • 1

克隆类型

  • 61
  • 3
多克隆

标记

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This Annexin VII antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human ANXA7

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Annexin VII (ANXA7) (Annexin A7 (ANXA7))

    别名

    ANXA7

    背景

    Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.

    UniProt

    P20073
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