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PKM 抗体

This anti-PKM antibody is a 兔 多克隆 antibody detecting PKM in ELISA, WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7234564
发货至: 中国

Quick Overview for PKM 抗体 (ABIN7234564)

抗原

See all PKM 抗体
PKM (Pyruvate Kinase M1/2 (PKM))

适用

  • 47
  • 12
  • 6
  • 5
人, 小鼠, 大鼠

宿主

  • 44
  • 7
  • 3

克隆类型

  • 42
  • 12
多克隆

标记

  • 36
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PKM antibody is un-conjugated

应用范围

  • 36
  • 32
  • 24
  • 19
  • 11
  • 9
  • 5
  • 2
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human PKM2

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.6 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PKM (Pyruvate Kinase M1/2 (PKM))

    别名

    PKM

    背景

    This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

    分子量

    58 kDa

    UniProt

    P14618

    途径

    Warburg Effect
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