CD147 抗体
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北京 101111
Quick Overview for CD147 抗体 (ABIN7234142)
抗原
See all CD147 (BSG) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen Affinity Purification
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免疫原
- Recombinant Rat Basigin protein
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亚型
- IgG
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应用备注
- WB 1:1000-1:2000 IHC 1:100-1:300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
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别名
- BSG
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背景
- BSG,also named as 5F7,Basigin,EMMPRIN,TCSF and CD147,plays pivotal roles in spermatogenesis,embryo implantation,neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1,SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA,inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix,plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
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分子量
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Observed_MW: 30 kDa,40-60 kDa
Calculated_MW: 30 kDa,40-60 kDa
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UniProt
- P26453
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途径
- S100 Proteins
抗原
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