SIGLEC15 抗体 (AA 270-320)
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Quick Overview for SIGLEC15 抗体 (AA 270-320) (ABIN6992284)
抗原
See all SIGLEC15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-320
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纯化方法
- SIGLEC15 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-SIGLEC15 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human SIGLEC15. The immunogen is located within amino acids 270-320 of SIGLEC15.
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亚型
- IgG
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应用备注
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WB: 2 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SIGLEC15 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SIGLEC15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SIGLEC15 (Sialic Acid Binding Ig-Like Lectin 15 (SIGLEC15))
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别名
- SIGLEC15
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背景
- SIGLEC15 Antibody: Siglecs are vertebrate cell-surface lectins that recognize sialylated glycans and are involved in many physiological processes, such as glycoprotein turnover, cellular trafficking, and pathogen recognition. Most Siglecs are expressed on cells of the immune system. SIGLEC15 is a type-I transmembrane protein consisting of two immunoglobulin (Ig)-like domains, a transmembrane domain containing a lysine residue, and a short cytoplasmic tail. SIGLEC15 can interact with the activating adaptor molecules DAP12/10. Its activating signaling potential and unique preference for glycan recognition implies that SIGLEC15 may be involved in the immune surveillance of tumors and probably plays a conserved, regulatory role in the immune system of vertebrates.
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分子量
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Predicted: 36kD
Observed: 34-36kD kDa -
基因ID
- 284266
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NCBI登录号
- NP_998767
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UniProt
- Q6ZMC9
抗原
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