PDCD1LG2 抗体 (Extracellular Domain)
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Quick Overview for PDCD1LG2 抗体 (Extracellular Domain) (ABIN6992226)
抗原
See all PDCD1LG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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纯化方法
- PD-L2 Antibody is supplied as protein A purified IgG1.
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免疫原
- PD-L2 antibody was raised against the extracellular domain of human PD-L2.
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亚型
- IgG1
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应用备注
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PD-L2 antibody can be used for detection of PD-L2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples, Immunofluorescence in human samples and Flow Cytometry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PD-L2 Antibody is supplied in PBS containing 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PD-L2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
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别名
- PDL2
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背景
- PD-L2 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through and alternative receptor from PD-1.
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分子量
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Predicted: 30 kDa
Observed: 38 kDa -
基因ID
- 80380
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NCBI登录号
- NP_079515
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UniProt
- P9BQ51
抗原
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