Vinculin 抗体 (N-Term) (Biotin)
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- 抗原 See all Vinculin (VCL) 抗体
- Vinculin (VCL)
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 兔, 小鸡
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Vinculin antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- Biotin-Vinculin antibody is human, mouse, rat, rabbit and chicken reactive. At least three isoforms of Vinculin are known to exist.
- 纯化方法
- Biotin-Vinculin antibody is affinity chromatography purified via peptide column.
- 免疫原
- Biotin-Vinculin antibody was raised against a 23 amino acid peptide near the amino terminus of human Vinculin.
- 亚型
- IgG
- Top Product
- Discover our top product VCL Primary Antibody
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- 应用备注
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Vinculin antibody can be used for detection of Vinculin by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Biotin-Vinculin Antibody is supplied in PBS containing 1 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Biotin-Vinculin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- Vinculin (VCL)
- 别名
- Vinculin (VCL 产品)
- 别名
- CMD1W antibody, CMH15 antibody, MV antibody, MVCL antibody, VCL antibody, im:6902790 antibody, hm:zehn2160 antibody, DDBDRAFT_0186762 antibody, DDBDRAFT_0232320 antibody, DDB_0186762 antibody, DDB_0232320 antibody, 9430097D22 antibody, AA571387 antibody, AI462105 antibody, AW545629 antibody, CG3299 antibody, CT11081 antibody, Dmel\\CG3299 antibody, Dmvincp antibody, EG:103B4.1 antibody, Vin antibody, Vin2EF antibody, vinc antibody, LOC100228062 antibody, vcl-A antibody, vinculin antibody, vinculin a antibody, vinculin A antibody, Vinculin antibody, vinculin S homeolog antibody, VCL antibody, vcla antibody, vinA antibody, Vcl antibody, Vinc antibody, CpipJ_CPIJ013873 antibody, Bm1_37935 antibody, vcl antibody, vcl.S antibody
- 背景
- Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).
- 分子量
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Predicted: 117 kDa
Observed: 117 kDa - 基因ID
- 7414
- NCBI登录号
- NP_003364
- UniProt
- P18206
- 途径
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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