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MLXIP 抗体 (N-Term)

This anti-MLXIP antibody is a 兔 多克隆 antibody detecting MLXIP in ELISA 和 WB. Suitable for 人.
产品编号 ABIN6992189
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MLXIP 抗体 (N-Term) (ABIN6992189)

抗原

See all MLXIP 抗体
MLXIP (MLX Interacting Protein (MLXIP))

适用

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宿主

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克隆类型

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多克隆

标记

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This MLXIP antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)
  • 抗原表位

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    N-Term

    纯化方法

    MLXIP Antibody is affinity chromatography purified via peptide column.

    免疫原

    MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.

    亚型

    IgG
  • 应用备注

    MLXIP antibody can be used for Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    MLXIP Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    MLXIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    MLXIP (MLX Interacting Protein (MLXIP))

    别名

    MLXIP

    背景

    MLXIP Antibody: MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).

    分子量

    Predicted: 20 kDa

    Observed: 21 kDa

    基因ID

    22877

    NCBI登录号

    NP_055753

    UniProt

    Q9HAP2
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