MLXIP 抗体 (N-Term)
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北京 101111
Quick Overview for MLXIP 抗体 (N-Term) (ABIN6992189)
抗原
See all MLXIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- MLXIP Antibody is affinity chromatography purified via peptide column.
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免疫原
- MLXIP antibody was raised against a peptide corresponding to 19 amino acids near the amino terminus of human MLXIP.
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亚型
- IgG
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应用备注
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MLXIP antibody can be used for Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MLXIP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MLXIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MLXIP (MLX Interacting Protein (MLXIP))
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别名
- MLXIP
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背景
- MLXIP Antibody: MLXIP is a member of the Myc superfamily of transcription factors and functions as part of a heterodimer with Max-like protein X (MLX) to activate transcription (1). MLXIP contributes to the regulation of glucose homeostasis as the MLXIP/MLX heterodimer activates expression of thioredoxin-interacting protein (TXNIP), a potent inhibitor of cellular glucose uptake and aerobic glycolysis. The mammalian target of rapamycin (mTOR) suppresses the activation of the TXNIP pathway by binding to MLXIP, thereby preventing the MLXIP/MLX heterodimer formation (2). MLXIP interaction with Myc may also be involved in metabolic reprogramming and tumorigenesis (3).
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分子量
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Predicted: 20 kDa
Observed: 21 kDa -
基因ID
- 22877
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NCBI登录号
- NP_055753
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UniProt
- Q9HAP2
抗原
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