Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
特异性
ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.
纯化方法
ALSFTD Antibody is affinity chromatography purified via peptide column.
免疫原
ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD. The immunogen is located within amino acids 400 - 450 of ALSFTD.
C9ORF72
适用: 人, 大鼠, 小鼠
WB, FACS, IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 555
应用备注
ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
ALSFTD Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
ALSFTD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
C9ORF72
(Chromosome 9 Open Reading Frame 72 (C9ORF72))
CZH9orf72 antibody, ALSFTD antibody, FTDALS antibody, AI840585 antibody, c9orf72 antibody, chromosome Z C9orf72 homolog antibody, chromosome 9 open reading frame 72 antibody, RIKEN cDNA 3110043O21 gene antibody, similar to RIKEN cDNA 3110043O21 antibody, chromosome 9 open reading frame 72 L homeolog antibody, CZH9orf72 antibody, C9orf72 antibody, 3110043O21Rik antibody, RGD1359108 antibody, c9orf72.L antibody
背景
ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).