IL-11 抗体 (N-Term)
Quick Overview for IL-11 抗体 (N-Term) (ABIN6992179)
抗原
See all IL-11 (IL11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90, N-Term
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特异性
- IL-11 antibody is human specific. At least two isoforms of IL-11 are known to exist, this antibody will only detect the longest isoform of IL-11.
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纯化方法
- IL-11 Antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-11 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-11. The immunogen is located within amino acids 40 - 90 of IL-11.
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亚型
- IgG
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anti-Interleukin 11 (IL11) (AA 22-199) antibody
IL11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 22-120) antibodyIL11 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 27-61) antibodyIL11 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56890 unconjugated
anti-Interleukin 11 (IL11) antibody (Biotin)IL11 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 11 (IL11) (AA 25-74) antibodyIL11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Interleukin 11 (IL11) (AA 25-199) antibodyIL11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (N-Term) antibodyIL11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IL-11 antibody can be used for the detection of IL-11 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-11 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IL-11 (IL11) (Interleukin 11 (IL11))
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别名
- IL-11
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背景
- Interleukin 11 is a pleiotropic cytokine that has multiple effects on both hematopoietic and nonhematopoietic cells. Many of the biological effects described for IL-11 overlap those for IL-6 (1). It directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (2). IL-11 promotes the proliferation of hepatocytes in response to liver damage. IL-11 binds to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 (3). Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelo-suppressive chemotherapy (4).
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分子量
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Predicted: 20 kDa
Observed: 19 kDa -
基因ID
- 3589
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NCBI登录号
- NP_000632
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UniProt
- P20809
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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