HOOK3 抗体 (N-Term)
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Quick Overview for HOOK3 抗体 (N-Term) (ABIN6992177)
抗原
See all HOOK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-260, N-Term
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特异性
- HOOK3 antibody is human, mouse and rat reactive. HOOK3 antibody is predicted to not cross-react with HOOK1 and HOOK2.
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纯化方法
- HOOK3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- HOOK3 antibody was raised against a 19 amino acid peptide from near the amino terminus of human HOOK3. The immunogen is located within amino acids 210 - 260 of HOOK3.
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亚型
- IgG
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应用备注
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HOOK3 antibody can be used for the detection of HOOK3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry at 10 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- HOOK3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- HOOK3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- HOOK3 (Hook Homolog 3 (HOOK3))
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别名
- HOOK3
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背景
- The HOOK proteins (HOOK1, HOOK2 and HOOK3) comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules mediating the spatial organization of diverse membrane-trafficking systems, their more divergent C-terminal domains mediate binding to organelles (1,2). HOOK3 exists as a homodimer and participates in defining the architecture and localization of the Golgi complex through its central coiled-coil domain (3). HOOK3 may regulate clearance of endocytosed receptors such as MSR1 (3,4).
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分子量
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Predicted: 79 kDa
Observed: 77 kDa -
基因ID
- 84376
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NCBI登录号
- NP_115786
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UniProt
- Q86VS8
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途径
- Stem Cell Maintenance, Maintenance of Protein Location
抗原
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