JAGN1 抗体 (C-Term)
JAGN1
适用: 人, 小鼠, 大鼠
ELISA, WB, IHC (p)
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all JAGN1 抗体
- JAGN1 (Jagunal Homolog 1 (JAGN1))
- 抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This JAGN1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- JAGN1 antibody is human, mouse and rat reactive. At least four isoforms of JAGN1 are known to exist, this antibody will detect all but isoform 2.
- 纯化方法
- JAGN1 antibody is affinity chromatography purified via peptide column.
- 免疫原
- JAGN1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human JAGN1. The immunogen is located within the last 50 amino acids of JAGN1.
- 亚型
- IgG
- Top Product
- Discover our top product JAGN1 Primary Antibody
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anti-Jagunal Homolog 1 (JAGN1) (AA 1-39) antibody
JAGN1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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JAGN1 antibody can be used for detection of JAGN1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- JAGN1 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- JAGN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- JAGN1 (Jagunal Homolog 1 (JAGN1))
- 别名
- JAGN1 (JAGN1 产品)
- 别名
- GL009 antibody, 5830427H10Rik antibody, zgc:101070 antibody, wu:fb07b07 antibody, zgc:101045 antibody, jagunal homolog 1 antibody, jagunal homolog 1 L homeolog antibody, jagunal homolog 1a antibody, jagunal homolog 1b antibody, JAGN1 antibody, Jagn1 antibody, jagn1.L antibody, jagn1a antibody, jagn1b antibody
- 背景
- JAGN1 is the human ortholog of a gene originally identified in Drosophila melanogaster. It is a transmembrane protein that functions in the early secretory pathway and is necessary for neutrophil differentiation and survival. Individuals with mutations in the JAGN1 gene causes aberrant myeloid cell homeostasis and severe congenital neutropenia (SCN) (1). JAGN1-mutant granulocytes are characterized by ultrastructural defects, aberrant N-glycosylation of multiple proteins, and increased apoptosis (1). Mice lacking this gene could not mount and efficient neutrophil-dependent immune response to a human fungal pathogen (2).
- 分子量
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Predicted: 20 kDa
Observed: 25 kDa - 基因ID
- 84522
- NCBI登录号
- NP_115881
- UniProt
- Q8N5M9
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