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RNF121 抗体 (C-Term)

This anti-RNF121 antibody is a 兔 多克隆 antibody detecting RNF121 in WB, ELISA 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6992161
发货至: 中国

Quick Overview for RNF121 抗体 (C-Term) (ABIN6992161)

抗原

See all RNF121 抗体
RNF121 (Ring Finger Protein 121 (RNF121))

适用

  • 9
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
人, 大鼠, 小鼠

宿主

  • 6
  • 3

克隆类型

  • 7
  • 2
多克隆

标记

  • 9
This RNF121 antibody is un-conjugated

应用范围

  • 9
  • 4
  • 4
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 260-310, C-Term

    特异性

    RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.

    纯化方法

    RNF121 antibody is affinity chromatography purified via peptide column.

    免疫原

    RNF121 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RNF121. The immunogen is located within amino acids 260 - 310 of RNF121.

    亚型

    IgG
  • 应用备注

    RNF121 antibody can be used for detection of RNF121 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    RNF121 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    RNF121 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    RNF121 (Ring Finger Protein 121 (RNF121))

    别名

    RNF121

    背景

    RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).

    分子量

    Predicted: 24, 27, 36 kDa

    Observed: 28 kDa

    基因ID

    552978

    NCBI登录号

    NP_060790

    UniProt

    Q9H920

    途径

    ER-Nucleus Signaling
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