RNF121 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for RNF121 抗体 (C-Term) (ABIN6992161)
抗原
See all RNF121 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 260-310, C-Term
-
特异性
- RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.
-
纯化方法
- RNF121 antibody is affinity chromatography purified via peptide column.
-
免疫原
- RNF121 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RNF121. The immunogen is located within amino acids 260 - 310 of RNF121.
-
亚型
- IgG
-
-
-
-
应用备注
-
RNF121 antibody can be used for detection of RNF121 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- RNF121 antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- RNF121 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- RNF121 (Ring Finger Protein 121 (RNF121))
-
别名
- RNF121
-
背景
- RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).
-
分子量
-
Predicted: 24, 27, 36 kDa
Observed: 28 kDa -
基因ID
- 552978
-
NCBI登录号
- NP_060790
-
UniProt
- Q9H920
-
途径
- ER-Nucleus Signaling
抗原
-