RNF121 抗体 (C-Term)
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- 抗原 See all RNF121 抗体
- RNF121 (Ring Finger Protein 121 (RNF121))
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抗原表位
- AA 260-310, C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF121 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
- 特异性
- RNF121 antibody is human, mouse and rat reactive. Multiple isoforms of RNF121 are known to exist.
- 纯化方法
- RNF121 antibody is affinity chromatography purified via peptide column.
- 免疫原
- RNF121 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human RNF121. The immunogen is located within amino acids 260 - 310 of RNF121.
- 亚型
- IgG
- Top Product
- Discover our top product RNF121 Primary Antibody
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- 应用备注
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RNF121 antibody can be used for detection of RNF121 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry at 10 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- RNF121 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- RNF121 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- RNF121 (Ring Finger Protein 121 (RNF121))
- 别名
- RNF121 (RNF121 产品)
- 背景
- RNF121 is an evolutionarily conserved E3 ligase ring finger protein that is expressed in the endoplasmic reticulum (1). It acts downstream of the unfolded protein response regulator protein kinase-like endoplasmic reticulum kinase (PERK). Overexpression of RNF121 during the early stages of gonad development led to aberrations in germline development and gonad migration, suggesting that it plays a role in endoplasmic reticulum-associated degradation machinery (1).
- 分子量
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Predicted: 24, 27, 36 kDa
Observed: 28 kDa - 基因ID
- 552978
- NCBI登录号
- NP_060790
- UniProt
- Q9H920
- 途径
- ER-Nucleus Signaling
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