IZUMO1 抗体 (AA 170-220)
Quick Overview for IZUMO1 抗体 (AA 170-220) (ABIN6992154)
抗原
See all IZUMO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-220
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特异性
- IZUMO1 antibody is human specific. At least four isoforms of IZUMO1 are known to exist, this antibody will detect the two longest isoforms.
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纯化方法
- IZUMO1 antibody is affinity chromatography purified via peptide column.
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免疫原
- IZUMO1 antibody was raised against an 18 amino acid peptide near the center of human IZUMO1. The immunogen is located within amino acids 170 - 220 of IZUMO1.
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亚型
- IgG
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anti-Izumo Sperm-Egg Fusion 1 (IZUMO1) antibody
IZUMO1 适用: 人, 小鼠 WB, IF, IP 宿主: 大鼠 Monoclonal #125 unconjugated
anti-Izumo Sperm-Egg Fusion 1 (IZUMO1) (AA 22-292) antibodyIZUMO1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Izumo Sperm-Egg Fusion 1 (IZUMO1) (C-Term) antibodyIZUMO1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Izumo Sperm-Egg Fusion 1 (IZUMO1) (C-Term) antibodyIZUMO1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IZUMO1 antibody can be used for detection of IZUMO1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IZUMO1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IZUMO1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IZUMO1 (Izumo Sperm-Egg Fusion 1 (IZUMO1))
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别名
- IZUMO1
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背景
- IZUMO1, a sperm-specific protein, is essential for sperm-egg plasma membrane binding and fusion. It is involved in the fertilization process and in the fusion of the sperm with the egg (1,2). IZUMO1 is expressed as at least four isoforms produced by alternative splicing and contains one Ig-like (immunoglobulin-like) C2-type domain (3). Lack of IZUMO1 in males, due to homozygous mutation in the gene that encodes IZUMO1, results in sterility due to an inability to penetrate the plasma membrane of the egg (4).
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分子量
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Predicted: 35, 39, 42 kDa
Observed: 52 kDa -
基因ID
- 284359
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NCBI登录号
- NP_872381
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UniProt
- Q8IYV9
抗原
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