QSOX1 抗体 (AA 360-410)
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Quick Overview for QSOX1 抗体 (AA 360-410) (ABIN6992133)
抗原
See all QSOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 360-410
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特异性
- QSOX1 antibody is human and mouse reactive. QSOX1 antibody is predicted to not cross-react with QSOX2.
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纯化方法
- QSOX1 antibody is affinity chromatography purified via peptide column.
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免疫原
- QSOX1 antibody was raised against a 17 amino acid peptide near the center of human QSOX1. The immunogen is located within amino acids 360 - 410 of QSOX1.
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亚型
- IgG
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应用备注
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QSOX1 antibody can be used for detection of QSOX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- QSOX1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- QSOX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- QSOX1 (Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1))
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别名
- QSOX1
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背景
- The QSOX1 gene, also known as Quiescin Q6, is a fusion of two ancient genes: thioredoxin and ERV1. Its expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation (1). The QSOX1 protein oxidizes sulfhydryl groups to form disulfide bonds in proteins. QSOX1 expression is induced by hypoxia (2) and appears to protect cells against oxidative stress-induced apoptosis (3).
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分子量
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Predicted: 65, 82 kDa
Observed: 66 kDa -
基因ID
- 5768
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NCBI登录号
- NP_002817
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UniProt
- O00391
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途径
- Cell RedoxHomeostasis
抗原
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