HOPX 抗体 (N-Term)
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Quick Overview for HOPX 抗体 (N-Term) (ABIN6992122)
抗原
See all HOPX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- HOPX antibody is human specific. At least three isoforms of HOPX are known to exist, this antibody will detect all three isoforms.
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纯化方法
- HOPX antibody is affinity chromatography purified via peptide column.
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免疫原
- HOPX antibody was raised against a 16 amino acid peptide near the amino terminus of human HOPX. The immunogen is located within the first 50 amino acids of HOPX.
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亚型
- IgG
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应用备注
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HOPX antibody can be used for detection of HOPX by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- HOPX antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- HOPX antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- HOPX (HOP Homeobox (HOPX))
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别名
- HOPX
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背景
- HOPX is a small homeodomain protein that lacks normally conserved residues required for DNA binding (1). It is thought to act downstream of NKX2-5 and modulates serum response factor (SRF)-dependent cardiac-specific gene expression and cardiac development (1). HOPX also acts a tumor suppressor gene in multiple tumors and cancer cell lines (2,3). HOPX has been reported to regulate the proliferation/differentiation homeostasis in different cell types, including keratinocytes (4).
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分子量
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Predicted: 12 kDa
Observed: 18 kDa -
基因ID
- 84525
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NCBI登录号
- NP_001138932
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UniProt
- Q9BPY8
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途径
- Regulation of Muscle Cell Differentiation
抗原
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