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ADRM1 抗体 (AA 210-260)

This anti-ADRM1 antibody is a 兔 多克隆 antibody detecting ADRM1 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6992113
发货至: 中国

Quick Overview for ADRM1 抗体 (AA 210-260) (ABIN6992113)

抗原

See all ADRM1 (Adrm1) 抗体
ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ADRM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 210-260

    特异性

    ADRM1 antibody is human, mouse and rat reactive. At least two isoforms of ADRM1 are know to exist, this antibody will detect both isoforms.

    纯化方法

    ADRM1 antibody is affinity chromatography purified via peptide column.

    免疫原

    ADRM1 antibody was raised against a 19 amino acid peptide near the center of human ADRM1. The immunogen is located within amino acids 210 - 260 of ADRM1.

    亚型

    IgG
  • 应用备注

    ADRM1 antibody can be used for detection of ADRM1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ADRM1 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ADRM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

    别名

    ADRM1

    背景

    The adhesion-regulating molecule 1 (ADRM1) is thought to be involved in protein recruitment and cell adhesion and functions as a proteasomal ubiquitin receptor (1). ADRM1 promotes the activity of UCH-L5 and plays a role in lymphocyte homing. The carboxy-terminal domain of mammalian ADRM1 serves to bind and enhance the isopeptidase activity of UCHL5/UCH37, perhaps serving as a mechanism to accelerate ubiquitin chain disassembly (2,3). ADRM1 expression is induced by IFN-gamma in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis (4,5).

    分子量

    Predicted: 45 kDa

    Observed: 48 kDa

    基因ID

    11047

    NCBI登录号

    NP_783163

    UniProt

    Q16186

    途径

    Positive Regulation of Endopeptidase Activity
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