ADRM1 抗体 (AA 210-260)
Our Local Distributor
北京 101111
Quick Overview for ADRM1 抗体 (AA 210-260) (ABIN6992113)
抗原
See all ADRM1 (Adrm1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 210-260
-
特异性
- ADRM1 antibody is human, mouse and rat reactive. At least two isoforms of ADRM1 are know to exist, this antibody will detect both isoforms.
-
纯化方法
- ADRM1 antibody is affinity chromatography purified via peptide column.
-
免疫原
- ADRM1 antibody was raised against a 19 amino acid peptide near the center of human ADRM1. The immunogen is located within amino acids 210 - 260 of ADRM1.
-
亚型
- IgG
-
-
-
-
应用备注
-
ADRM1 antibody can be used for detection of ADRM1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- ADRM1 antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- ADRM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))
-
别名
- ADRM1
-
背景
- The adhesion-regulating molecule 1 (ADRM1) is thought to be involved in protein recruitment and cell adhesion and functions as a proteasomal ubiquitin receptor (1). ADRM1 promotes the activity of UCH-L5 and plays a role in lymphocyte homing. The carboxy-terminal domain of mammalian ADRM1 serves to bind and enhance the isopeptidase activity of UCHL5/UCH37, perhaps serving as a mechanism to accelerate ubiquitin chain disassembly (2,3). ADRM1 expression is induced by IFN-gamma in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis (4,5).
-
分子量
-
Predicted: 45 kDa
Observed: 48 kDa -
基因ID
- 11047
-
NCBI登录号
- NP_783163
-
UniProt
- Q16186
-
途径
- Positive Regulation of Endopeptidase Activity
抗原
-