Adenosine A2b Receptor 抗体 (C-Term)
Quick Overview for Adenosine A2b Receptor 抗体 (C-Term) (ABIN6992110)
抗原
See all Adenosine A2b Receptor (ADORA2B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ADORA2B antibody is human, mouse and rat reactive. At least two isoforms of ADORA2B are known to exist, this antibody will detect both isoforms. ADORA2B antibody is predicted to not cross-react with ADORA2A.
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纯化方法
- ADORA2B antibody is affinity chromatography purified via peptide column.
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免疫原
- ADORA2B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human ADORA2B. The immunogen is located within the last 50 amino acids of ADORA2B.
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亚型
- IgG
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anti-Adenosine A2b Receptor (ADORA2B) (C-Term) antibody
Verified ADORA2B 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (AA 292-332) antibodyADORA2B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (AA 251-300) antibodyADORA2B 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (AA 101-200) antibodyADORA2B 适用: 人, 小鼠, 大鼠 WB, FACS, IF (p), IHC (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (AA 147-166), (C154S), (Extracellular) antibodyADORA2B 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (AA 100-200) antibodyADORA2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (C-Term) antibodyADORA2B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (N-Term) antibodyADORA2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (AA 233-282) antibodyADORA2B 适用: 人, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adenosine A2b Receptor (ADORA2B) (AA 147-166), (C154S), (Extracellular) antibody (FITC)ADORA2B 适用: 人 FACS 宿主: 兔 Polyclonal FITC
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应用备注
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ADORA2B antibody can be used for detection of ADORA2B by Western blot at 0.25 - 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ADORA2B antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ADORA2B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Adenosine A2b Receptor (ADORA2B)
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别名
- ADORA2B
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背景
- The adenosine receptor ADORA2B is a member of the G protein-coupled receptor superfamily and is an integral membrane protein that stimulates adenylate cyclase activity in the presence of adenosine (1,2). Extracellular adenosine triggers a potent anti-inflammatory response that is mediated in part by ADORA2B including the stimulation of IL-10 production (3-5). Activation of ADORA2B can also enhance the abundance of regulatory T cells (Tregs), a class of cells that work to constrain inflammation (6).
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分子量
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Predicted: 37 kDa
Observed: 41 kDa -
基因ID
- 136
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NCBI登录号
- NP_000667
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UniProt
- P29275
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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