Ectodysplasin A 抗体 (AA 130-180)
Quick Overview for Ectodysplasin A 抗体 (AA 130-180) (ABIN6992088)
抗原
See all Ectodysplasin A (EDA) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-180
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特异性
- EDA1 antibody is human, mouse and rat reactive. Multiple isoforms of EDA1 are known to exist.
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纯化方法
- EDA1 antibody is affinity chromatography purified via peptide column.
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免疫原
- EDA1 antibody was raised against an 19 amino acid peptide near the center of human EDA1. The immunogen is located within amino acids 130 - 180 of EDA1.
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亚型
- IgG
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应用备注
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EDA1 antibody can be used for detection of EDA1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- EDA1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- EDA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Ectodysplasin A (EDA)
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别名
- EDA1
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背景
- Ectodysplasin A (EDA1) is a member of the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation (1). It is a trimeric type II membrane protein that co-localizes with cytoskeletal structures at the lateral and apical surfaces of cells and can be expressed as eight alternatively spliced isoforms in hair follicles and in the epidermis of adult skin (2,3). EDAs are required during development, and loss or mutation of EDA1 results in a group of developmental disorders identified as ectodermal dysplasia type 1 (4,5).
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分子量
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Predicted: 16, 43 kDa
Observed: 39 kDa -
基因ID
- 1896
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NCBI登录号
- NP_001390
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UniProt
- Q92838
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途径
- Tube Formation
抗原
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