KLF17 抗体 (C-Term)
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北京 101111
Quick Overview for KLF17 抗体 (C-Term) (ABIN6992086)
抗原
See all KLF17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- KLF17 antibody is human, mouse and rat reactive. At least two isoforms of KLF17 are known to exist, this antibody will only detect the large isoform. KLF17 antibody is predicted to not cross-react with other KLF proteins.
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纯化方法
- KLF17 antibody is affinity chromatography purified via peptide column.
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免疫原
- KLF17 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KLF17. The immunogen is located within the last 50 amino acids of KLF17.
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亚型
- IgG
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应用备注
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KLF17 antibody can be used for detection of KLF17 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- KLF17 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- KLF17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- KLF17 (Kruppel-Like Factor 17 (KLF17))
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别名
- KLF17
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背景
- KLF17, also known as ZNF393, is a member of the Sp/KLF family of transcription factors (1,2). KLF17 binds to the promoter and negatively regulates the transcription of Id-1, a key metastasis regulator in breast cancer (3). Suppression of KLF17 promotes breast cancer cell invasion and epithelial-mesenchymal transition (3). Down-regulated KLF17 expression is also associated tumor invasion and poor prognosis in hepatocellular carcinoma, suggesting that the level of KLF17 expression can serve as a prognostic indicator (4).
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分子量
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Predicted: 28, 39, 43 kDa
Observed: 38 kDa -
基因ID
- 128209
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NCBI登录号
- NP_775755
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UniProt
- Q5JT82
抗原
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