NOSTRIN 抗体 (C-Term)
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Quick Overview for NOSTRIN 抗体 (C-Term) (ABIN6992085)
抗原
See all NOSTRIN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 430-480, C-Term
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特异性
- NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist, this antibody will detect all four isoforms.
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纯化方法
- NOSTRIN antibody is affinity chromatography purified via peptide column.
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免疫原
- NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN. The immunogen is located within amino acids 430 - 480 of NOSTRIN.
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亚型
- IgG
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应用备注
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NOSTRIN antibody can be used for detection of NOSTRIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NOSTRIN antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NOSTRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- NOSTRIN (Nitric Oxide Synthase Trafficker (NOSTRIN))
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别名
- NOSTRIN
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背景
- NOSTRIN. also known as endothelial nitric oxide synthase traffic inducer, is a member of the Pombe Cdc15 homology (PCH) family of proteins which may function as the modulator of the subcellular localisation and activity of endothelial nitric oxide synthase (eNOS) (1,2). It decreases NOS3 activity by inducing its translocation away from the plasma membrane (3). NOSTRIN typically exists as a trimer and is expressed in the vascular endothelial cells of highly vascularized tissues such as placenta, lung, kidney and heart. NOSTRIN is necessary for proper vascular development in zebrafish and postnatal retinal angiogenesis in mice (4,5).
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分子量
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Predicted: 47, 53, 56, 62 kDa
Observed: 68 kDa -
基因ID
- 115677
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NCBI登录号
- NP_443178
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UniProt
- Q8IVI9
抗原
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