WWC1 抗体 (N-Term)
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Quick Overview for WWC1 抗体 (N-Term) (ABIN6992072)
抗原
See all WWC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-110, N-Term
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特异性
- WWC1 antibody is human, mouse and rat reactive. At least three isoforms of WWC1 are known to exist, this antibody will detect all three isoforms.
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纯化方法
- WWC1 antibody is affinity chromatography purified via peptide column.
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免疫原
- WWC1 antibody was raised against an 18 amino acid peptide near the amino terminus of human WWC1. The immunogen is located within amino acids 60 - 110 of WWC1.
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亚型
- IgG
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应用备注
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WWC1 antibody can be used for detection of WWC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- WWC1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- WWC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- WWC1 (WW and C2 Domain Containing 1 (WWC1))
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别名
- WWC1
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背景
- The WW and C2 domain containing 1 (WWC1) protein, also known as KIBRA, possesses two WW domains and an internal C2-like domain (1). WWC1 was originally identified as a memory performance-associated protein in humans (2) and has recently been shown to be a novel regulator of the Hippo pathway (3). WWC1 is phosphorylated by the mitotic kinases Aurora-A and -B (4), and in turn activates the Aurora kinases and is required for precise chromosome alignment during mitosis (5).
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分子量
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Predicted: 123 kDa
Observed: 110 kDa -
基因ID
- 23286
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NCBI登录号
- NP_001155133
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UniProt
- Q8IX03
抗原
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