Neuroligin 2 抗体 (C-Term)
Quick Overview for Neuroligin 2 抗体 (C-Term) (ABIN6992063)
抗原
See all Neuroligin 2 (NLGN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 630-680, C-Term
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特异性
- NLGN2 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. NLGN2 antibody is predicted to not cross-react with other members of the NLGN protein family.
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纯化方法
- NLGN2 antibody is affinity chromatography purified via peptide column.
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免疫原
- NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2. The immunogen is located within amino acids 630 - 680 of NLGN2.
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亚型
- IgG
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anti-Neuroligin 2 (NLGN2) (Internal Region) antibody
Verified NLGN2 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Neuroligin 2 (NLGN2) (AA 657-670), (Extracellular) antibodyNLGN2 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Neuroligin 2 (NLGN2) (AA 15-180) antibodyNLGN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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NLGN2 antibody can be used for detection of NLGN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NLGN2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NLGN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Neuroligin 2 (NLGN2)
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别名
- NLGN2
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背景
- Neuroligin 2 (NLGN2) is a member of a family of neuronal cell surface proteins that localize to the post-synaptic membrane (1,2). Neuroligins are thought to act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses (2). NLGN2 has been shown to control perisomatic inhibitory synapse maturation together with gephyrin and collybistin, thereby regulating GABA receptor clustering on neurons (3,4). NLGN2 also exhibits differential functions at different types of inhibitory synapses on the same postsynaptic neuron (5).
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分子量
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Predicted: 92, 99 kDa
Observed: 80, 97 kDa -
基因ID
- 57555
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NCBI登录号
- NP_065846
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UniProt
- Q8NFZ4
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途径
- Cell-Cell Junction Organization, Synaptic Membrane
抗原
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