VEZT 抗体 (AA 480-530)
Our Local Distributor
北京 101111
Quick Overview for VEZT 抗体 (AA 480-530) (ABIN6992059)
抗原
See all VEZT 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 480-530
-
特异性
- VEZT antibody is human, mouse and rat reactive. Multiple isoforms are known to exist.
-
纯化方法
- VEZT antibody is affinity chromatography purified via peptide column.
-
免疫原
- VEZT antibody was raised against a 17 amino acid peptide near the center of human VEZT. The immunogen is located within amino acids 480 - 530 of VEZT.
-
亚型
- IgG
-
-
-
-
应用备注
-
VEZT antibody can be used for detection of VEZT by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- VEZT antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- VEZT antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- VEZT (Vezatin, Adherens Junctions Transmembrane Protein (VEZT))
-
别名
- VEZT
-
背景
- Vezatin (VEZT) is a transmembrane protein which localizes to adherens junctions and binds to myosin VIIA and the cadherin-catenins complex (1). Expression of this gene in gastric cancer tissues is decreased due to hypermethylation of the promoter. Expression of this gene may also be inhibited by binding of a specific microRNA to a target sequence in the 3' UTR of the transcripts (2). VEZT has also been shown to be required for morphogenesis of the preimplantation mouse embryo (3).
-
分子量
-
Predicted: 63, 68, 78, 81, 83, 86 kDa
Observed: 60 kDa -
基因ID
- 55591
-
NCBI登录号
- NP_060069
-
UniProt
- Q9HBM0
抗原
-