TXNIP 抗体 (AA 110-160)
Quick Overview for TXNIP 抗体 (AA 110-160) (ABIN6992052)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-160
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特异性
- TXNIP antibody is human, mouse and rat reactive.
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纯化方法
- TXNIP antibody is affinity chromatography purified via peptide column.
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免疫原
- TXNIP antibody was raised against a 16 amino acid peptide near the center of human TXNIP. The immunogen is located within amino acids 110 - 160 of TXNIP.
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亚型
- IgG
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anti-Thioredoxin Interacting Protein (TXNIP) (AA 30-381) antibody
TXNIP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-166) antibodyTXNIP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 32-367) antibodyTXNIP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 1-30), (N-Term) antibodyTXNIP 适用: 人 WB 宿主: 兔 Polyclonal RB41554 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 116-145) antibodyTXNIP 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB30652 unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (Internal Region) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 101-200) antibodyTXNIP 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (C-Term) antibodyTXNIP 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 猴, Bat, Pig, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thioredoxin Interacting Protein (TXNIP) (AA 299-381) antibodyTXNIP 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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TXNIP body can be used for detection of TXNIP by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry at 2 μ,g/mL. For Immunoflorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TXNIP antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TXNIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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别名
- TXNIP
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背景
- Thioredoxin-interacting protein (TXNIP) belongs to the arrestin family and plays a critical role in the antioxidant defense mechanisms of hematopoietic cells by activating the p53 pathway during oxidative stress (1,2). It functions as a transcriptional repressor and acts as an oxidative stress mediator by inhibiting thioredoxin activity (2). TXNIP expression is reduced in many types of tumors, and TXNIP overexpression inhibits tumor growth by blocking cell-cycle progression (3). It has recently reported that TXNIP deficiency correlates with a high incidence of hepatocellular carcinoma (HCC) (4). TXNIP and p53 interactions could potentially be a therapeutic target for oxidative stress-related diseases such as hematopoietic malignancies and metabolic diseases (5).
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分子量
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Predicted: 43 kDa
Observed: 39 kDa -
基因ID
- 10628
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NCBI登录号
- NP_006463
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UniProt
- Q9H3M7
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途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
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