BAMBI 抗体 (AA 100-150)
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北京 101111
Quick Overview for BAMBI 抗体 (AA 100-150) (ABIN6992047)
抗原
See all BAMBI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-150
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特异性
- BAMBI antibody is human, mouse and rat reactive.
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纯化方法
- BAMBI antibody is affinity chromatography purified via peptide column.
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免疫原
- BAMBI antibody was raised against a 17 amino acid peptide near the center of human BAMBI. The immunogen is located within amino acids 100 - 150 of BAMBI.
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亚型
- IgG
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应用备注
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BAMBI antibody can be used for detection of BAMBI by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BAMBI antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BAMBI antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
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别名
- BAMBI
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背景
- BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development (1). BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4 (2,3). BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues (4). BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines (5).
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分子量
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Predicted: 29 kDa
Observed: 26 kDa -
基因ID
- 25805
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NCBI登录号
- NP_036474
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UniProt
- Q13145
抗原
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