PDCL3 抗体 (C-Term)
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Quick Overview for PDCL3 抗体 (C-Term) (ABIN6992031)
抗原
See all PDCL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- PDCL3 antibody is human, mouse and rat reactive. PDCL3 antibody is predicted to not cross-react with other members of the PDCL protein family.
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纯化方法
- PDCL3 antibody is affinity chromatography purified via peptide column.
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免疫原
- PDCL3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human PDCL3. The immunogen is located within the last 50 amino acids of PDCL3.
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亚型
- IgG
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应用备注
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PDCL3 antibody can be used for detection of PDCL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PDCL3 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PDCL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- PDCL3 (Phosducin-Like 3 (PDCL3))
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别名
- PDCL3
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背景
- Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1,2). PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain (3). Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding (4). Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling (5).
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分子量
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Predicted: 26 kDa
Observed: 25 kDa -
基因ID
- 79031
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NCBI登录号
- NP_076970
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UniProt
- Q9H2J4
抗原
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