MFN2 抗体 (AA 250-300)
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北京 101111
Quick Overview for MFN2 抗体 (AA 250-300) (ABIN6992022)
抗原
See all MFN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-300
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特异性
- MFN2 antibody is human, mouse and rat reactive. At least three isoforms of MFN2 are known to exist. MFN2 antibody is predicted to not cross-react with MFN1.
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纯化方法
- MFN2 antibody is affinity chromatography purified via peptide column.
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免疫原
- MFN2 antibody was raised against a 17 amino acid peptide near the center of human MFN2. The immunogen is located within amino acids 250 - 300 of MFN2.
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亚型
- IgG
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anti-Mitofusin 2 (MFN2) (AA 661-757) antibody
MFN2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Mitofusin 2 (MFN2) (AA 1-120) antibodyMFN2 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 500-600) antibodyMFN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 687-757) antibodyMFN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 447-476) antibodyMFN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (N-Term) antibodyMFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibodyMFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 unconjugated
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (HRP)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 HRP
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (FITC)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 FITC
anti-Mitofusin 2 (MFN2) (AA 370-600) antibody (Biotin)MFN2 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S153-5 Biotin
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应用备注
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MFN2 antibody can be used for detection of MFN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MFN2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MFN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- MFN2 (Mitofusin 2 (MFN2))
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别名
- MFN2
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背景
- Mitofusin 2 (MFN2) and the related protein MFN1 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN2 is ubiquitously expressed, and found in both the ER and outer mitochondrial membrane. MFN2 has two key domains: a coiled coil region that mediates MFN2 binding and a GTPase domain that likely plays a role in fusion (3,4). Both domains are essential for embryonic development and may play a role in the pathobiology of obesity. Overexpression of MFN2 causes mitochondrial dysfunction and cell death (5).
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分子量
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Predicted: 83 kDa
Observed: 90 kDa -
基因ID
- 9927
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NCBI登录号
- NP_055689
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UniProt
- O95140
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途径
- Skeletal Muscle Fiber Development
抗原
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