DOCK8 抗体 (C-Term)
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北京 101111
Quick Overview for DOCK8 抗体 (C-Term) (ABIN6992016)
抗原
See all DOCK8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DOCK8 antibody is human, mouse and rat reactive. Multiple isoforms of DOCK8 are known to exist.
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纯化方法
- DOCK8 antibody is affinity chromatography purified via peptide column.
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免疫原
- DOCK8 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human DOCK8. The immunogen is located within the last 50 amino acids of DOCK8.
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亚型
- IgG
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应用备注
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DOCK8 antibody can be used for detection of DOCK8 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DOCK8 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DOCK8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DOCK8 (Dedicator of Cytokinesis 8 (DOCK8))
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别名
- DOCK8
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背景
- The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors (1). DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse (reviewed in 2). Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome (3).
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分子量
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Predicted: 166, 220, 231 kDa
Observed: 220, 230 kDa -
基因ID
- 81704
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NCBI登录号
- NP_982272
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UniProt
- Q8NF50
抗原
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