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Vinculin 抗体 (C-Term)

Name: Vinculin 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN6992009
Availability: OutOfStock

This anti-Vinculin antibody is a 兔多克隆 antibody detecting Vinculin in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠和大鼠.

产品编号 ABIN6992009

发货至: 中国

Quick Overview for Vinculin 抗体 (C-Term) (ABIN6992009)

抗原

See all Vinculin (VCL) 抗体

Vinculin (VCL)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Vinculin antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product VCL Primary Antibody

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AA 1060-1110, C-Term

特异性

Vinculin antibody is human, mouse and rat specific. At least three isoforms of Vinculin are known to exist.

纯化方法

Vinculin Antibody is affinity chromatography purified via peptide column.

免疫原

Anti-Vinculin antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human Vinculin. The immunogen is located within amino acids 1060-1110 of Vinculin.

亚型

IgG
anti-Vinculin (VCL) (AA 1-1066) antibody
VCL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C6-1B5 unconjugated

anti-Vinculin (VCL) (AA 879-1064) antibody
VCL 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) (AA 903-937) antibody
VCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55983 unconjugated

anti-Vinculin (VCL) (AA 1020-1134) antibody
VCL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) (AA 634-668) antibody
VCL 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB55982 unconjugated

anti-Vinculin (VCL) (AA 1-1066) antibody
VCL 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3F8-1D4 unconjugated

anti-Vinculin (VCL) (AA 174-322) antibody
VCL 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VCL-2575 unconjugated

anti-Vinculin (VCL) (AA 174-322) antibody
VCL 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal VCL-2572 unconjugated

anti-Vinculin (VCL) (AA 767-1066) antibody
VCL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Vinculin (VCL) antibody
VCL 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

应用备注

WB: 1-2 μ,g/mL, IHC: 5 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in rat samples, Immunofluorescence in rat samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Vinculin Antibody is supplied in PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

Vinculin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原

Vinculin (VCL)

别名

Vinculin

背景

Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development (1). Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail (2). Expression of vinculin were shown to be affected by the level of actin expression (2,3). Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth (4). Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W) (5).

分子量

Predicted: 124kD

Observed: 124kD kDa

基因ID

7414

NCBI登录号

NP_003364

UniProt

P18206

途径

Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2