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OASL 抗体 (N-Term)

This anti-OASL antibody is a 兔 多克隆 antibody detecting OASL in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991998
发货至: 中国

Quick Overview for OASL 抗体 (N-Term) (ABIN6991998)

抗原

See all OASL 抗体
OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This OASL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    N-Term

    特异性

    OASL antibody is human, mouse and rat reactive.

    纯化方法

    OASL antibody is affinity chromatography purified via peptide column.

    免疫原

    OASL antibody was raised against a 17 amino acid peptide near the amino terminus of human OASL. The immunogen is located within the first 50 amino acids of OASL.

    亚型

    IgG
  • 应用备注

    OASL antibody can be used for detection of OASL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 2.5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    OASL Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    OASL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))

    别名

    OASL

    背景

    OASL (2'-5'-oligoadenylate synthetase-like), also known as p59OASL or TRIP14 (thyroid receptor-interacting protein 14), is a 514 amino acid protein that exists as two alternatively spliced isoforms, designated p56 and p30, and contains two ubiquitin-like domains (1). It is widely expressed in a variety of tissues and interacts with the ligand binding domain of the thyroid receptor (TR) and is able to bind double-stranded RNA and DNA, possibly playing a role in RNA degradation and the overall inhibition of protein synthesis (2-3). Methyl CpG-binding protein 1 (MBD1), which functions as a transcriptional repressor, was identified as a strong p59 OASL interactor (4).

    分子量

    Predicted: 57 kDa

    Observed: 65 kDa

    基因ID

    8638

    NCBI登录号

    NP_003724

    UniProt

    Q15646
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