OASL 抗体 (N-Term)
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北京 101111
Quick Overview for OASL 抗体 (N-Term) (ABIN6991998)
抗原
See all OASL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- OASL antibody is human, mouse and rat reactive.
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纯化方法
- OASL antibody is affinity chromatography purified via peptide column.
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免疫原
- OASL antibody was raised against a 17 amino acid peptide near the amino terminus of human OASL. The immunogen is located within the first 50 amino acids of OASL.
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亚型
- IgG
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应用备注
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OASL antibody can be used for detection of OASL by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 2.5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- OASL Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- OASL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- OASL (2'-5'-Oligoadenylate Synthetase-Like (OASL))
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别名
- OASL
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背景
- OASL (2'-5'-oligoadenylate synthetase-like), also known as p59OASL or TRIP14 (thyroid receptor-interacting protein 14), is a 514 amino acid protein that exists as two alternatively spliced isoforms, designated p56 and p30, and contains two ubiquitin-like domains (1). It is widely expressed in a variety of tissues and interacts with the ligand binding domain of the thyroid receptor (TR) and is able to bind double-stranded RNA and DNA, possibly playing a role in RNA degradation and the overall inhibition of protein synthesis (2-3). Methyl CpG-binding protein 1 (MBD1), which functions as a transcriptional repressor, was identified as a strong p59 OASL interactor (4).
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分子量
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Predicted: 57 kDa
Observed: 65 kDa -
基因ID
- 8638
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NCBI登录号
- NP_003724
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UniProt
- Q15646
抗原
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