IFIT1 抗体 (C-Term)
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Quick Overview for IFIT1 抗体 (C-Term) (ABIN6991993)
抗原
See all IFIT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-340, C-Term
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特异性
- IFIT1 antibody is human, mouse and rat reactive. At least three isoforms of IFIT1 are known to exist. This antibody is predicted to not cross-react with other members of the IFIT protein family.
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纯化方法
- IFIT1 antibody is affinity chromatography purified via peptide column.
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免疫原
- IFIT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT1. The immunogen is located within amino acids 290 - 340 of IFIT1.
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亚型
- IgG
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应用备注
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IFIT1 antibody can be used for detection of IFIT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IFIT1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IFIT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))
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别名
- IFIT1
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背景
- The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3).
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分子量
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Predicted: 53 kDa
Observed: 53 kDa -
基因ID
- 3434
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NCBI登录号
- NP_001539
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UniProt
- P09914
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途径
- Hepatitis C
抗原
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