Density Regulated Protein 抗体 (AA 80-130)
Quick Overview for Density Regulated Protein 抗体 (AA 80-130) (ABIN6991992)
抗原
See all Density Regulated Protein (DENR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-130
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特异性
- DENR antibody is human, mouse and rat reactive.
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纯化方法
- DENR antibody is affinity chromatography purified via peptide column.
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免疫原
- DENR antibody was raised against an 18 amino acid peptide near the center of human DENR. The immunogen is located within amino acids 80 - 130 of DENR.
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亚型
- IgG
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应用备注
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DENR antibody can be used for detection of DENR by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DENR Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DENR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))
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别名
- DEN
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背景
- DENR (density-regulated protein), also designated DRP or smooth muscle cell associated protein 3 (SMAP-3), is a 198 amino acid protein that may be involved in the translation of target mRNAs by scanning and recognition of the initiation codon (1). It plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1 (2,3). DENR contains a SUI1 domain and is found in a variety of tissues with highest levels present in skeletal and cardiac muscle. It is up-regulated in ovarian and breast cancer cells by ERBB2 overexpression (4).
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分子量
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Predicted: 22 kDa
Observed: 22 kDa -
基因ID
- 8562
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NCBI登录号
- NP_003668
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UniProt
- O43583
抗原
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