TET1 抗体 (C-Term)
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Quick Overview for TET1 抗体 (C-Term) (ABIN6991985)
抗原
See all TET1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2030-2080, C-Term
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特异性
- TET1 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with TET2 and TET3.
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纯化方法
- TET1 antibody is affinity chromatography purified via peptide column.
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免疫原
- TET1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET1. The immunogen is located within amino acids 2030 - 2080 of TET1.
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亚型
- IgG
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anti-Tet Methylcytosine Dioxygenase 1 (TET1) (AA 2038-2136) antibody
TET1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4F4 unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (AA 1700-1800) antibodyTET1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (AA 1845-1879), (C-Term) antibodyTET1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52496 unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (C-Term) antibodyTET1 适用: 人, 小鼠 WB, IHC, ChIP, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 1 (TET1) (C-Term) antibodyTET1 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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TET1 antibody can be used for detection of TET1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TET1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TET1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))
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别名
- TET1
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背景
- TET1, a member of the ten-eleven-translocation (TET) family of genes, was initially discovered as a fusion partner of MLL in acute myeloid leukemias containing the t(10,11)(q22,q23) (1). It is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine (2). TET1 expression is regulated during inflammation in both THP-1 and primary dendritic cells, and is a negative transcriptional regulator of IL-1beta following and inflammatory stimulus (3). Recent evidence has shown that TET1 is part of a signaling pathway that regulates breast cancer growth and metastasis (4).
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分子量
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Predicted: 235 kDa
Observed: 240 kDa -
基因ID
- 80312
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NCBI登录号
- NP_085128
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UniProt
- Q8NFU7
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途径
- Stem Cell Maintenance, Warburg Effect
抗原
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