TRF2 抗体 (N-Term)
Quick Overview for TRF2 抗体 (N-Term) (ABIN6991982)
抗原
See all TRF2 (TERF2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- TERF2 antibody is human specific.
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纯化方法
- TERF2 antibody is affinity chromatography purified via peptide column.
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免疫原
- TERF2 antibody was raised against a 17 amino acid peptide near the amino terminus of human TERF2. The immunogen is located within the first 50 amino acids of TERF2.
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亚型
- IgG
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anti-Telomeric Repeat Binding Factor 2 (TERF2) (AA 324-500) antibody
TERF2 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 3H6B4 unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) (AA 78-238) antibodyTERF2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) antibodyTERF2 适用: 人, 小鼠, 大鼠, Deer WB, ELISA, IHC, IP, ICC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 4A794-15 unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) (AA 144-438) antibodyTERF2 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) antibodyTERF2 适用: 人, 小鼠 WB, IHC, IP, IHC (p), ChIP 宿主: 山羊 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) (AA 81-287) antibodyTERF2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) antibodyTERF2 适用: 人 WB, ELISA, IHC, IP, IF, ChIP, FACS, FM 宿主: 小鼠 Monoclonal 4A794-15 unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) (AA 1-251) antibodyTERF2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) (C-Term) antibodyTERF2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, Pig, 非洲爪蟾, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Telomeric Repeat Binding Factor 2 (TERF2) (C-Term) antibodyTERF2 适用: 人, 小鼠, 大鼠, 犬, Cow, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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TERF2 antibody can be used for detection of TERF2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TERF2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TERF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))
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别名
- TERF2
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背景
- The telomeric repeat binding factor family (TERF1 and TERF2) plays a key role in cellular immortalization and cellular senescence (1). TERF2, as a component of the telomere nucleoprotein complex, is present at telomeres in metaphase of the cell cycle (2). TERF2 is a second negative regulator of telomere length and binds as a dimer to TTAGGG repeats at ends of chromosomes (telomeres), where it blocks inappropriate activation of the ATM/p53 pathway (2,3). TERF1 negatively regulates telomere elongation, while TERF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression (4,5).
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分子量
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Predicted: 60 kDa
Observed: 69 kDa -
基因ID
- 7014
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NCBI登录号
- NP_005643
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UniProt
- Q15554
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途径
- Cell Division Cycle, Telomere Maintenance
抗原
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